Copa America Centenario aka 100th edition of Copa America is heading towards the knockout stage and quarterfinals are scheduled to begin from June 16. Four quarter-final matches will be played between 16 and 18 June 2016 meanwhile semi-finals are set to be played on 21 and 22 June. Final of 2016 Copa America to take place on 26th June.
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Quarter-Final Line-ups
| Date | Time | Match | Fixture | Result |
| 16 June | 21:30 | 1st Quarter-Final | United States vs Ecuador | USA won by 2-1 |
| 17 June | 20:00 | 2nd Quarter-Final | Peru vs Colombia | Colombia won by 4-2 (Penalties) |
| 18 June | 19:00 | 3rd Quarter-Final | Argentina vs Venezuela | Argentina won by 4-1 |
| 18 June | 22:00 | 4th Quarter-Final | Mexico vs Chile | Chile won by 7-0 |
Semi-Final Line-ups
Winners of all four quarter-finals will be playing semi-finals on 21st and 22nd June at Houston and Chicago respectively.
| Date | Time | Match | Fixture | Venue |
| 21 June | 21:00 | 1st Semi-Final | USA vs Argentina | NRG Stadium, Houston |
| 22 June | 20:00 | 2nd Semi-Final | Colombia vs Chile | Soldier Field, Chicago |
